Januvia is a pill taken once a day to help lower blood sugar levels in adults with type two diabetes.

Januvia works by increasing the insulin made by your pancreas when blood sugar is high, and by reducing the amount of sugar made by your liver.

Between October 2006 and February 2009, the FDA (Food and Drug Administration) received 88 post-marketing cases of acute pancreatitis, including two cases of hemorrhagic or necrotizing pancreatitis 21% of which occurred within 30 days of starting Januvia.  As well, just over half of the cases were resolved once Januvia was discontinued.

In Sept of 2009, the FDA issued a revision to the warning label of Januvia to include side effects, such as Januvia pancreatitis and Januvia cancer.

Pancreatitis – Is a condition in which the pancreas becomes inflamed.  The pancreas is a large gland behind the stomach and close to the duodenum.  The pancreas secretes enzymes into the duodenum through a tube called the pancreatic duct.  The pancreas also releases the hormones insulin and glucagon into the bloodstream.

UCLA researchers found that Januvia caused abnormalities in the pancreas that are recognized as risk factors for pancreatitis and pancreatic cancer.  While taking Januvia the pancreas may becomes inflamed altering its normal structure and functions.

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